许旭东,中国医学科学院药用植物研究所中药资源化学三级实验室主任,研究方向为中药及民族药药效物质基础,纯天然绿色植物消杀、化妆产品的研发,国家食品药品监督管理局化妆品审评,国家自然科学基金函评,科技部国际科技合作计划评审,科技部中小企业创新基金评审,教育部学位与研究生教育评审,教育部留学回国人员科研启动基金评审专家,中国中药协会杜仲专业委员会常务委员,北京市药学会天然药物分会委员。主持国家和省部级项目10余项,作为子课题负责人参加国家和省部级项目20余项。参加工作以来共发表论文180多篇,其中SCI论文120多篇,编写出版学术专著4部。获得授权国家发明专利23项。2018年“几种海南热带特色药用植物化学和生物活性成分研究”获海南省自然科学奖三等奖,2016年“瑶药组分库构建及其中八种特色瑶药的物质基础新发现”的研究工作获广西科学技术奖三等奖;2016年 “传统傣药雅糯妙(肾茶)药理活性及药效物质基础研究”获云南西双版纳傣族自治州科学技术进步一等奖。
代表性论文:
1. De-Li Chen1, Guo-Xu Ma1, Er-Lan Yang, Yun Yang, Can-Hong Wang, Zhao-Cui Sun, Han-Qiao Liang, Xu-Dong Xu *, Jian-He Wei *. Cadinane-type sesquiterpenoid dimeric diastereomers hibisceusones A-C from infected stems of Hibiscus tiliaceus with cytotoxic activity against triple-negative breast cancer cells. Bioorganic Chemistry, 2022, 127: 105982.
2. De-Li Chen, Mei-Ying Chen, Yong Hou, Can-Hong Wang, Zhao-Cui Sun, Yun Yang, Han-Qiao Liang, Guo-Xu Ma*, Xu-Dong Xu*, Jian-He Wei*. Cadinane-type sesquiterpenoids with cytotoxic activity from the infected stems of the semi-mangrove Hibiscus tiliaceus. Journal of Natural Products, 2022, 85, 127-135.
3. Yong Hou, Linjun Zou, Qinglong Li, Meiying Chen, Haonan Ruan, Zhaocui Sun, Xudong Xu **, Junshan Yang, Guoxu Ma*. Supramolecular assemblies based on natural small molecules: Union would be effective. Materials Today Bio, 2022, 15: 100327.
4. Zhaocui Sun1, Meiying Chen1, Qinglong Li, Guoxu Ma, Haifeng Wu, Junshan Yang, Yihang Li*, Xudong Xu*. Five new polyoxypregnaneglycosides from the vines of Aspidopterys obcordate and their antinephrolithiasis activity. Molecules, 2022, 27(14): 4596.
5. Yong Hou, Qinglong Li, Meiying Chen, Haifeng Wu, Jungshan Yang, Zhaocui Sun*, Xudong Xu*, MaGuoxu*. Novel geranylhydroquinone derived meroterpenoids from the fungus Clitocybe clavipes and their cytotoxic activity. Fitoterapia, 2022, 161:105251.